Effect of Filler and Slip Casting Methods with Nano TiO₂ Anatase as Anti-Candida Albicans on Extraoral Maxillofacial Prostheses: A Laboratory Experiment
Keywords:
Filler and Slip Casting Methods, Nano TiO₂ Anatase, Anti-Candida Albicans, Extraoral MaxillofacialAbstract
Background: Extraoral maxillofacial prostheses using polyurethane material are currently widely used in various rehabilitation treatments after maxillofacial surgery. Among the advantages of polyurethane material, this material also has various weaknesses, including being easily attached to bacterial biofilms or Candida albicans which can cause material degradation and can cause disturbances in the balance of the oral microflora. One effort that can be made to prevent adhesion and colonization of Candida albicans on material surfaces is by improving surface properties using anatase titanium dioxide nanoparticles which have antimicrobial properties, especially against Candida albicans because they have photocatalytic properties that can inhibit the growth of Candida albicans colonies. This research aimed to determine the effect of applying anatase titanium dioxide (TiO₂) nanoparticles to polyurethane plates on the growth of Candida albicans biofilms.
Methods: The design of this research is experimental laboratory research. Subjects were divided into two groups, namely: the treatment group and the control group. The treatment groups were divided into two types of treatment, namely the addition group using the anatase nano-titanium dioxide filler method (1, 2, 3, and 4%), and the surface coating group using the anatase nano titanium dioxide slip casting method (1, 2, 3, and 4%). Candida albicans was cultured and grown to form a biofilm on polyurethane plates in each group.
Results: Treatment with polyurethane surface coating using 4% nano titanium dioxide anatase using the slip casting method showed the lowest number of Candida albicans colonies.
Conclusion: Nano titanium dioxide anatase (TiO₂) surface coating on polyurethane plates is the most treatment that can inhibit Candida albicans biofilm formation.
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